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Grants starting October 2001

Projects funded from October 2001

Location: Aston University, England
Project Title: Molecular analyses of human craniopharyngiomas
Funds Awarded: £59,537

Location: University of North Carolina at Chapel Hill, United States of America
Project Title: Role of p53 Inactivation in the Suppresssion of Breast Cancer by Dietary Antioxidant Depletion in Genetically Engineered Mice
Funds Awarded: £188,066

Location: The Babraham Institute
Project Title: Identification and characteristics of novel effectors of survival pathways mediated by Protein Kinase B in lymphocytes
Funds Awarded: £139,212

Location: Oxford University, England
Project Title: Characterisation of the FOXP1 transcription factor, a novel candidate tumour suppressor gene
Funds Awarded: £110,076

Location: University of Glasgow, Scotland
Project Title: Functional Analyses of Novel Human Herpesvirus 8 Interferon Regulatory Factor Homologues
Funds Awarded: £150,481

Location: University of York, England
Project Title: Fluorescent semiconductor nanocrystals as a breakthrough technology for ultra-sensitive detection of human DNA topoisomerases - targets for anti-cancer chemotherapy.
Funds Awarded: £95,090

Location: The University of Reading, England
Project Title: DNA binding modes of toposiomerase poisons
Funds Awarded: £49,250

Location: Addenbrooke's NHS Trust, England
Project Title: Early detection of colorectal adenocarcinoma using antibodies against minichromosome maintenance proteins
Funds Awarded: £39,619

Location: University College London, England
Project Title: The Role of T(11;18)(q21;q21) in Malt Lymphoma Development
Funds Awarded: £147,910

Location: CRC Beatson Laboratories, Scotland
Project Title: Identification of a mortality gene on human chromosome 6 by functional and positional cloning
Funds Awarded: £129,416

Location: University of Tübingen, Germany
Project Title: Molecular mechanisms of tumor cell apoptosis
Funds Awarded: £145,500

Location: The University of Durham, England
Project Title: The Role of LAP2 alpha in Cell Proliferation
Funds Awarded: £139,948

Location: Leiden University Medical Center, The Netherlands
Project Title: A structure- function analysis of the Mdmx protein
Funds Awarded: £131,470

Location: Erasmus University Rotterdam, The Netherlands
Project Title: Structural and Functional Analysis of the Xrcc4 and DNA Ligae IV DNA Double-Strand Break Repair Proteins
Funds Awarded: £132,400

Location: University of Dundee, Scotland
Project Title: Postranscriptional regulation of p14SARF. Development of a superactive p14ARF tumour suppressor protein.
Funds Awarded: £77,306

Location: University of Edinburgh, Scotland
Project Title: Prevention of ultraviolet radiation (UV)-induced skin cancers by dietary selenium. A study to define the optimum form and dose of selenium for protection.
Funds Awarded: £54,891

Location: Marie Curie Research Institute
Project Title: Regulation of general transcription factor TFIID activity via SUMO-1 modification.
Funds Awarded: £129,460

Location: Washington University
Project Title: Nuclear exclusion of p53 in human cancers
Funds Awarded: £93,014

Location: Ben Gurion University, Israel
Project Title: The role of the F-box receptor Ym1088w in the DNA damage response
Funds Awarded: £48,000

Location: University of Birmingham, England
Project Title: Functional analysis of the PATCHED gene in basal cell carcinoma
Funds Awarded: £122,683

Location: Newcastle University, England
Project Title: Modulation of Androgen Receptor-Mediated Cellular Signalling in Human Prostate Cancer by the Coactivator Protein TIP60
Funds Awarded: £114,538

Location: Marie Curie Research Institute
Project Title: Uncoupling the ATPase of kinesin
Funds Awarded: £36,587

Location: International Agency for Research on Cancer
Project Title: Randomised intervention trial to evaluate oral visual inspection in the control of oral cancer
Funds Awarded: £97,057

Location: University of Zurich, Switzerland
Project Title: Thymine DNA glycosylase in Repair of Mutagenic DNA Base Damage and Tumor Suppression
Funds Awarded: £114,501

Location: Imperial College of Science, Technology & Medicine
Project Title: Use of MHC-peptide fusion molecules for generation of allo-restricted cytotoxic T cells
Funds Awarded: £142,986

Location: University of Manchester, England
Project Title: Identification of tumour suppressor gene(s) on chromosome 8p23 implicated in oral squamous cell carcinomas
Funds Awarded: £107,082

Location: University of Bath, England
Project Title: Towards a polymeric prodrug system for selective delivery of cytotoxins to prostate tumours
Funds Awarded: £58,720

Location: University of Manchester, England
Project Title: Role of JNK in alkylating agent-induced apoptosis and its significance in the prevention of carcinogenesis
Funds Awarded: £127,046

Location: University of Wales College of Medicine, Wales 
Project Title: Identification of somatic mutational events in NF1 tumorigenesis
Funds Awarded: £60,600

Location: Imperial College of Science, Technology & Medicine
Project Title: In vivo positron emission tomography imaging of oestrogen-regulated gene expression in breast cancer
Funds Awarded: £155,860

Location: University of Glasgow, Scotland
Project Title: Deregulation of TFIIIC2 in Transformed Cells
Funds Awarded: £106,979

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