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Grants starting October 2000

Projects funded from 1 October 2000

Location: Medical Research Council
Project Title: Proteins required for centromere-kinetochore function in fission yeast
Funds Awarded: £132,723

Location: University of Dundee, Scotland
Project Title: Regulation of the Cyclin Dependent Kinase Inhibitor p21 by Reversible Phosphorylation
Funds Awarded: £110,477

Location: Imperial College of Science, Technology & Medicine
Project Title: Investigation into the role of corepressors in antiandrogen action and androgen-independent prostate cancer
Funds Awarded: £141,864

Location: National Medical Laser Centre
Project Title: Photodynamic Therapy for the treatment of Barrett's Oesophagus
Funds Awarded: £114,121

Location: University of Dundee, Scotland
Project Title: Identification of novel cellular factors that interact with the HTLV-1 Tax transactivator and isolation of inhibitors of Tax function
Funds Awarded: £58,265

Location: University of St Andrews, Scotland
Project Title: Transgenic mouse models for studying a role of synucleins in malignancy
Funds Awarded: £136,675

Location: Erasmus University Rotterdam, The Netherlands
Project Title: Identification of proteins interacting with GC79, a novel zinc finger protein, implicated in prostate cancer cell apoptosis
Funds Awarded: £125,933

Location: University of Manchester, England
Project Title: The role of nitric oxide synthase in the metabolism and activation of bioreductive drugs in cancer therapy
Funds Awarded: £131,009

Location: Uppsala University, Sweden
Project Title: Identification of intracellular signalling pathways which regulate angiogenesis
Funds Awarded: £85,500

Location: Cardiff University, Wales
Project Title: Analysing the predisposition to mammary neoplasia in a model of perturbed involution
Funds Awarded: £125,357

Location: Leiden University Medical Centre, The Netherlands
Project Title: Identification of E-cadherin mediated expression patterns involved in the development of lobular breast cancer
Funds Awarded: £100,674

Location: Leiden University Medical Centre, The Netherlands
Project Title: Biochemical characterisation of translesion synthesis in mammalian cells
Funds Awarded: £103,228

Location: National Institute for Medical Research
Project Title: Analysis of human papillomavirus type 16 E4-mediated cell cycle arrest
Funds Awarded: £122,985

Location: University of Glasgow, Scotland
Project Title: Development of inducible, melanocyte-specific knockout mice to analyse tumour suppressor gene loss and oncogene synergism in melanoma
Funds Awarded: £138,033

Location: The University of Kent at Canterbury, England
Project Title: Mechanisms of membrane clustering of the EFGR family of growth factor receptors using GFP tagging and digital microscopy
Funds Awarded: £129,122

Location: University of Oxford, England
Project Title: Functional role of the lymphatics in tumour dissemination
Funds Awarded: £108,988

Location: Imperial College of Science, Technology & Medicine
Project Title: Identification of mesenchymally derived growth regulators of human prostate epithelia using an improved secretion trap strategy
Funds Awarded: £136,301

Location: UMR CNRS 8601
Project Title: Binding of the antitumor drug cisplatin to GGG sequences of DNA: structural perturbation and recognition by the HMG domain of the transcription factor LEF-1
Funds Awarded: £74,650

Location: University of Patras, Greece
Project Title: Regulation of S-phase onset in fission yeast and human cells
Funds Awarded: £61,999

Location: University of Edinburgh, Scotland
Project Title: Analysis of the consequences of loss of APC gene function in the mammary gland
Funds Awarded: £33,000

Location: MRC Human Genetics Unit
Project Title: The role of the Wilms Tumour 1 (WT1) gene in leukaemia development
Funds Awarded: £120,331

Location: University of Reading, England
Project Title: Design and synthesis of tyrosinase activated prodrugs for the treatment of melanoma.
Funds Awarded: £38,079

Location: University of Zurich, Switzerland
Project Title: DNA interstrand crosslink repair in mammals
Funds Awarded: £118,026

Location: The University of Edinburgh, Scotland
Project Title: Regulation of integrin function and apoptosis by CD98 in small cell lung cancer
Funds Awarded: £138,554

Location: University of Wales, Wales
Project Title: High resolution time-lapse multiphoton imaging of anticancer drugs in living tumour cells: linking single cell pharmacokinetics, pharmacodynamics, tumour cell responses and treatment design through bioinformatics
Funds Awarded: £115,771

Location: IGBMC
Project Title: Identification and characterisation of proteins interacting with the EHF-CFC protein One-eyed pinhead
Funds Awarded: £116,940

Location: University of Bath, England
Project Title: Insulin-like growth factor 2: escape from imprinted regulation in both normal and tumour cells
Funds Awarded: £68,265

The Association for International Cancer Research funds projects all over the world. A donation from you, today, will contribute to further research into conquering cancer.


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