As AICR’s Scientific Co-ordinator, Dr Mark Matfield receives progress reports from AICR-funded scientists all over the world. Here you can watch some of these video updates from the world of prostate cancer research, giving you a fascinating insight into the vital work we are funding and what drives the scientists at the forefront of cancer research.
Dr Justin Sturge, Imperial College London, England
Predicting whether prostate cancer will spread
Advanced prostate cancer often spreads to the skeleton where it causes severe pain and the weakening of bones, leading to fractures and other problems. Dr Sturge has found increased levels of a protein, called Endo180, in the type of cancer that can move from the prostate gland to the bone. This suggests that it could be used for predicting if prostate cancer might spread. Endo180 could also be involved in the spreading process itself, so blocking its activity may help prevent prostate cancer moving to the bone. With his AICR grant Dr Sturge is studying how targeting Endo180 may help prevent the spreading process.