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Grants starting April 2007

Projects Funded from April 2007

Location:  European Institute of Oncology, Italy
Project Title:  Role of p31comet in the regulation and adaptation of the spindle assembly checkpoint
Funds Awarded: £90,047

Location:  Institute of Child Health, United Kingdom (England)
Project Title:  Role of CD44 and Rho GTPase signalling in cancer cell extravasation
Funds Awarded: £161,790

Location:  University of Crete, Greece
Project Title:  Immunomodulation by tumour –derived neuropeptides; the role of CRF peptide family in cancer
Funds Awarded: £82,127

Location:  Institute of Child Health, United Kingdom (England)
Project Title:  Regulation of the Brn-3a transcription factor by genetic and environmental factors and its role in HPV-induced cervical cancer.
Funds Awarded: £169,406

Location:  St. Vincent's Institute, Australia
Project Title:  A new mouse model of myeloid leukaemia
Funds Awarded: £184,798

Location:  Centre National de la Recherche Scientifique, France
Project Title:  Characterization of HIC1 transcriptional targets
Funds Awarded: £99,488

Location:  The FIRC Institute of Molecular Oncology Foundation, Italy
Project Title:  The role of VE-cadherin and beta catenin in angiogenesis
Funds Awarded: £100,983

Location:  University of Leicester, United Kingdom (England)
Project Title:  Regulation and function of the AP-1 family member, Fos-
related antigen-1 (Fra-1) in cancer cells.
Funds Awarded: £157,442

Location:  Institut Cochin, INSERM, France
Project Title:  IEX-1: a new actor in the ERK and PP2A signaling pathways.  Role in hematopoietic cells and involvement in acute myeloid leukemia
Funds Awarded: £72,984

Location:  Erasmus Medical Center, Netherlands
Project Title:  Wnt-Notch interactions in normal and malignant hematopoiesis
Funds Awarded: £185,463

Location:  Erasmus University Rotterdam, Netherlands
Project Title:  TFIIH stability and activities: contribution to carcinogenesis
Funds Awarded: £162,003

Location:  Marie Curie Research Institute, United Kingdom (England)
Project Title:  Identification and functional analysis of novel APC/C substrates and regulators
Funds Awarded: £156,401

Location:  Institut Curie, France
Project Title:  Involvement of the calcineurin/NFAT signaling pathway in    lymphoma/leukemogenesis
Funds Awarded: £120,094

Location:  University of Dundee, United Kingdom (Scotland)
Project Title:  Design of Neh2 mini-proteins that inhibit Keap1 and elicit a cancer chemopreventive antioxidant response in the absence of redox stress
Funds Awarded: £158,113

Location:  Umea University, Sweden
Project Title:  Discovery of new targeted interventions of Myc-induced cancer
Funds Awarded: £132,620

Location:  University of Glasgow, United Kingdom (Scotland)
Project Title:  The role of the chromatin unfolding protein HMGN1 in the cellular response to DNA damage
Funds Awarded: £156,653

Location:  MRC Laboratory of Molecular Biology, United Kingdom (England)
Project Title:  The role of SUMO in DNA repair
Funds Awarded: £149,576

Location:  University of Copenhagen, Copenhagen
Project Title:  Functional role of the JMJD2 histone demethylases in cell proliferation and cancer
Funds Awarded: £164,177

Location:  University Medical Center Utrecht, Netherlands
Project Title:  Tumour immune evasion from cellular immunity: a new role for collagen
Funds Awarded: £150,192

Location:  University of Sydney, Australia
Project Title:  LMO4-DEAF-1 interactions in cellular development and breast cancer
Funds Awarded: £39,456

Location:  Karolinska Institute, Sweden
Project Title:  Regulation of tumor cell growth and homotypic adhesion by UCH-L1
Funds Awarded: £133,134

Location:  The FIRC Institute of Molecular Oncology Foundation, Italy
Project Title:  Analysis of the mechanism of tumor-antigen cross-presentation induced by Salmonella typhimurium
Funds Awarded: £102,945

Location:  MRC Laboratory of Molecular Biology, United Kingdom (England)
Project Title:  Proteins interacting with the APC tumour suppressor
Funds Awarded: £195,807

Location:  Cleveland Clinic, Lerner Research Institute, United States
Project Title:  Identifying a novel Wilms’ tumour suppressor gene at 2q37
Funds Awarded: £85,079

Location:  Institute for Biomedical Research, Switzerland
Project Title:  Role of PTP1B in Breast Cancer
Funds Awarded: £139,903

Location:  Western General Hospital, United Kingdom (England)
Project Title:  Is WT1 an oncogene?
Funds Awarded: £167,009

Location:  The Hebrew University-Hadassah Medical School, Israel
Project Title:  Tumour development in the absence of the NK activating
receptor NCR1
Funds Awarded: £117,519

Location:  Kings College London, United Kingdom (England)
Project Title:  Does the muscle satellite cell constitute a cellular  source of alveolar  rhabdomyosarcoma?
Funds Awarded: £173,940

Location:  University of Texas Health Science Center, United States
Project Title:  Role of PTPRD in Neuroblastoma Pathogenesis
Funds Awarded: £136,425

Location:  Peter MacCallum Cancer Centre, Australia
Project Title:  Identification of cell surface proteins that dictate site specific metastasis of breast cancer
Funds Awarded: £133,628

Location:  University of Dundee, United Kingdom (Scotland)
Project Title:  Regulation of IKK function following Hypoxia
Funds Awarded: £148,646

Location:  VU University Medical Center, Netherlands
Project Title:  Recognition of glycosylated tumor antigens by C-type lectins on DC to enhance anti-tumor responses
Funds Awarded: £166,969

By funding only the best science, we ensure that we have the highest chance of making significant progress.  Applications for funding are peer reviewed by our Scientific Advisory Committee and many are also sent to two experts in the field for external review.

 

 

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