Projects funded from 1 April 2002
Location: University of Madrid, Spain
Project Title: Modulation of ras-mediated proliferation, tumorigenesis and senescence by thyroid hormone and retinoic acid receptors
Funds Awarded: £75,990
Location: Ludwig Institute for Cancer Research
Project Title: Genetic and cell biological analysis of the involvement in tumorigenesis of Mutated in Colorectal Cancer and Rho GTPase signalling
Funds Awarded: £133,660
Location: University of Bristol, England
Project Title: Characterisation of a novel, potentially inhibitory isoform, of Vascular Endothelial Growth Factor
Funds Awarded: £102,237
Location: University of Leeds, England
Project Title: The role of the c-myb proto-oncogene in primitive and definitive haematopoiesis
Funds Awarded: £129,396
Location: Hebrew University of Jerusalem, Israel
Project Title: The role and regulation of the human securin/PTTG oncogene
Funds Awarded: £108,556
Location: Beatson Institute for Cancer Research, Scotland
Project Title: Investigation of the regulation of Scar family proteins by Src family tyrosine kinase: implications for colon cancer metastasis
Funds Awarded: £117,235
Location: Beatson Institute for Cancer Research, Scotland
Project Title: Characterisation of ETL1: A candidate tumour suppressor gene
Funds Awarded: £139,445
Location: The University of Edinburgh, Scotland
Project Title: Function of Ruk, a novel adaptor protein, in tumour cells
Funds Awarded: £118,212
Location: Glasgow University Veterinary School, Scotland
Project Title: An investigation of Runx 1 function in B-cell development and neoplasia
Funds Awarded: £122,306
Location: University of Aberdeen, Scotland
Project Title: Characterisation of G1/S molecular networks in colon tumours: Identification of pyrimidine metabolic and cell cycle pathways governing chemosensitivity and survival of colon cancer patients
Funds Awarded: £128,970
Location: University of Leicester, England
Project Title: Mitotic regulation of Nek2 protein kinase stability
Funds Awarded: £121,234
Location: Institute of Cancer Research
Project Title: Investigation into the Regulation of Tyrosine Phosphorylation on CDK4
Funds Awarded: £127,702
Location: University of Cambridge, England
Project Title: Human monoclonal antibodies to the MET receptor for cancer therapy
Funds Awarded: £124,080
Location: University of Manchester Institute of Science & Technology, England
Project Title: Signalling pathways and molecular mechanisms that control P16 INK4a tumour suppressor gene expression
Funds Awarded: £129,519
Location: University of Dundee, Scotland
Project Title: Contribution of Nrf2 and AhR to the actions of cancer chemopreventive blocking agents in human colon cells
Funds Awarded: £119,162
Location: University College London, England
Project Title: Identification of functional targets of the Kaposi sarcoma associated herpsevirus-encoded cyclin in proliferation and oncogenesis
Funds Awarded: £144,907
Location: The Queen's University of Belfast, Northern Ireland
Project Title: Design, synthesis and biological evaluation of novel inhibitors of the enzyme telomerase as potential anti-cancer drugs
Funds Awarded: £115,500
Location: Peter MacCallum Cancer Institute
Project Title: The role of hyaluronic acid in normal and leukaemic haemopoiesis
Funds Awarded: £123,711
Location: University College Dublin, Republic of Ireland
Project Title: Novel compounds for photodynamic therapy: Design, synthesis, in vitro evaluation and mechanistic studies
Funds Awarded: £45,150
Location: European Institute of Oncology
Project Title: Regulation of the tumour suppressor p53 by the Promyelocytic Protein (PML)
Funds Awarded: £103,500
Location: University of Newcastle, England
Project Title: Retinoid-regulated signalling pathways in medulloblastoma: potential for novel therapies
Funds Awarded: £101,901
Location:
Project Title: CNRS UPR-1086 The mechanism by which the Src-Like Adaptor Protein negatively regulates mitogenesis induced by growth factors
Funds Awarded: £102,915
Location: Garvan Institute of Medical Research
Project Title: Regulation of G1-S phase cell cycle progression by cyclin-dependent kinase-mediated phosphorylation of the ubiquitin-conjugating enzyme Cdc34
Funds Awarded: £93,909
Location: National Institue for Medical Research
Project Title: Structural and biochemical basis of Chk2 tumour suppressor kinase activation
Funds Awarded: £133,994
Location: University of Bath, England
Project Title: Natural anti-carcinogenic defence mechanisms and UV damage to skin-novel targets for protective strategies
Funds Awarded: £129,497
Location: Erasmus University Rotterdam, The Netherlands
Project Title: Macromolecular dynamics of DNA end-joining proteins in living cells.
Funds Awarded: £121,500
Location: University of Cambridge, England
Project Title: Molecular Mechanisms of Drug Transport by and Modulation of the Breast Cancer Resistance Protein
Funds Awarded: £114,199
Location: University of Toronto, Canada
Project Title: Function of DDR1 in mammary gland devlopment and breast cancer tumour invasion
Funds Awarded: £103,105
Location: Tel-Aviv University, Israel
Project Title: The Schizosaccharomyces pombe TOR homologues - cellular roles under normal and stress conditions
Funds Awarded: £97,500
