Projects funded from October 2007
Location: Indian Institute of Science, India
Project Title: Structural and functional studies of insulin-like growth factor binding proteins for developing novel IGF-antagonist based cancer therapeutics
Funds Awarded: £54,025
Location: Flanders Interuniversity, Belgium
Project Title: Targeting modifiers of the p53 tumor suppressor pathway as a new avenue for cancer therapy
Funds Awarded: £140,789
Location: University of Southampton, United Kingdom (England)
Project Title: Enhancing the immunogenicity of apoptotic tumour cells by masking phosphatidylserine recognition
Funds Awarded: £175,781
Location: University of Edinburgh, United Kingdom (Scotland)
Project Title: Gene-Environment Interactions in Melanoma Development
Funds Awarded: £184,138
Location: The University of Hong Kong, Hong Kong
Project Title: Centrosome overduplication and HTLV-1 leukemogenesis
Funds Awarded: £145,021
Location: University of Southampton, United Kingdom (England)
Project Title: Role of transcriptional control of HDMX expression in the regulation of the p53-dependent stress-response
Funds Awarded: £147,187
Location: Beatson Institute for Cancer Research, United Kingdom (Scotland)
Project Title: Invadopodia: degrading and protruding machinery working together to promote cancer metastasis
Funds Awarded: £148,142
Location: Leiden University Medical Center, Netherlands
Project Title: Genetic programs associated with enhanced effector function and survival of anti-tumour CTLs
Funds Awarded: £180,700
Location: University of Durham, United Kingdom (England)
Project Title: Investigation of the roles of lamin A/C and LAP2alpha in cell cycle progression and checkpoint control
Funds Awarded: £195,551
Location: University of Dundee, United Kingdom (Scotland)
Project Title: FKBP25: a novel regulator of the p53 pathway that promotes degradation of MDM2
Funds Awarded: £84,556
Location: Leeds University, United Kingdom (England)
Project Title: IRF4 and BLIMP1: defining a complex transcriptional switch in B-cell differentiation deregulated in lymphomagenesis
Funds Awarded: £158,558
Location: CNRS, France
Project Title: Genetic modifiers of cancer risk in BRCA1/2 mutation carriers: study of the effect of sequence variants in the genes involved in the nonsense-mediated mRNA decay pathway
Funds Awarded: £103,226
Location: University of Torino, Italy
Project Title: Role of p130Cas adaptor in estrogen receptor and Her2-Neu-mediated tumorigenesis
Funds Awarded: £112,500
Location: Fondazione Santa Lucia, Italy
Project Title: Role of Caspase-8 tyrosine phosphorylation by Src kinases in tumour progression and in tumor resistance to apotosis
Funds Awarded: £52,818
Location: Instituto Superiore di Sanita, Italy
Project Title: Analysis of alternative pathway activated by replication stress in the cancer-prone disease Werner syndrome: implications for a non-toxic therapy of cancer with specific defects in replication fork re
Funds Awarded: £128,526
Location: CNRS, France
Project Title: Regulation of the p53 family member, p63, by E4F1: Role in the renewal and transformation of stratified epithelia
Funds Awarded: £111,903
Location: University of Birmingham, United Kingdom (England)
Project Title: Extending Epstein-Barr virus tropism by transfer infection: mechanism, range and pathogenetic significance of viral transfer from the B cell surface.
Funds Awarded: £171,754
Location: University of Birmingham, United Kingdom (England)
Project Title: Identification of an inherited Wilms' tumour gene
Funds Awarded: £98,951
Location: Technical University Munich, Germany
Project Title: Development of IPMN lesions in a mouse model of pancreatic cancer
Funds Awarded: £128,518
Location: Peter MacCallum Cancer Centre, Australia
Project Title: Molecular characterization of the tumour suppressive properties of mammalian Scribble
Funds Awarded: £134,640
Location: BSRC Alexander Fleming, Greece
Project Title: The role of the post-transcriptional regulator HuR in neoplastic transformation and inflammatory modulation of intestinal cancers
Funds Awarded: £89,443
Location: University Medical Center Utrecht, Netherlands
Project Title: Identification of metastasis genes activated by oncogenic Kras(G12D)
Funds Awarded: £120,295
Location: Centre de Regulacio Genomica, Spain
Project Title: Function of oncogene / tumor suppressor gene products DEK, EWS and LUCA-15 in pre-mRNA splicing regulation
Funds Awarded: £112,103
Location: ACS Inserm Paris V Sainte Anne, France
Project Title: The immune response against dying tumour cells. The implication of TLR4
Funds Awarded: £101,939
Location: University Medical Center Utrecht, Netherlands
Project Title: The impact of human Regulatory T cells on the Graft versus Tumor effect
Funds Awarded: £155,579
Location: Netherlands Cancer Institute, Netherlands
Project Title: Genome-wide insertional mutagenesis screens to identify cancer genes that collaborate with E-cadherin loss in mammary tumourigenesis
Funds Awarded: £176,848
Location: Institute of Cancer Research, United Kingdom (England)
Project Title: Regulation of Apoptosome Assembly
Funds Awarded: £174,253
Location: Institut Pasteur, France
Project Title: Role of the SUMO Pathway in the Maintenance of Genomic Integrity
Funds Awarded: £92,025
Location: University of Bristol, United Kingdom (England)
Project Title: Alternative splice forms of VEGF in cancer – possible value in anti-VEGF therapy.
Funds Awarded: £158,904
Location: The International Agency for Research on Cancer, France
Project Title: Influence of TP53 gene status on the response of breast cancers to anti-hormone therapy
Funds Awarded: £125,300
Location: Erasmus Medical Center, Netherlands
Project Title: Clinical significance of microRNAs in breast cancer
Funds Awarded: £131,428
Location: Forschungszentrum Karlsruhe, Germany
Project Title: Inhibition of action of Bag-1L as a measure of preventing prostate cancer development and metastasis
Funds Awarded: £155,509
Location: Queens University Belfast, United Kingdom (Northern Ireland)
Project Title: Elucidating the importance of cancer cell-derived interleukin-8 in potentiating the bony metastasis of prostate cancer
Funds Awarded: £159,494
Location: University of Newcastle upon Tyne, United Kingdom (England)
Project Title: The Role of Histone Methyltransferase and Demethylase Enzymes in Androgen Receptor Regulation and Prostate Cancer.
Funds Awarded: £163,001
Location: University of Nottingham, United Kingdom (England)
Project Title: Regulation of cancer cell proliferation by the nuclear receptor corepressor Ccr4-Not
Funds Awarded: £147,333
Project Title: Structural and functional studies of insulin-like growth factor binding proteins for developing novel IGF-antagonist based cancer therapeutics
Funds Awarded: £54,025
Location: Flanders Interuniversity, Belgium
Project Title: Targeting modifiers of the p53 tumor suppressor pathway as a new avenue for cancer therapy
Funds Awarded: £140,789
Location: University of Southampton, United Kingdom (England)
Project Title: Enhancing the immunogenicity of apoptotic tumour cells by masking phosphatidylserine recognition
Funds Awarded: £175,781
Location: University of Edinburgh, United Kingdom (Scotland)
Project Title: Gene-Environment Interactions in Melanoma Development
Funds Awarded: £184,138
Location: The University of Hong Kong, Hong Kong
Project Title: Centrosome overduplication and HTLV-1 leukemogenesis
Funds Awarded: £145,021
Location: University of Southampton, United Kingdom (England)
Project Title: Role of transcriptional control of HDMX expression in the regulation of the p53-dependent stress-response
Funds Awarded: £147,187
Location: Beatson Institute for Cancer Research, United Kingdom (Scotland)
Project Title: Invadopodia: degrading and protruding machinery working together to promote cancer metastasis
Funds Awarded: £148,142
Location: Leiden University Medical Center, Netherlands
Project Title: Genetic programs associated with enhanced effector function and survival of anti-tumour CTLs
Funds Awarded: £180,700
Location: University of Durham, United Kingdom (England)
Project Title: Investigation of the roles of lamin A/C and LAP2alpha in cell cycle progression and checkpoint control
Funds Awarded: £195,551
Location: University of Dundee, United Kingdom (Scotland)
Project Title: FKBP25: a novel regulator of the p53 pathway that promotes degradation of MDM2
Funds Awarded: £84,556
Location: Leeds University, United Kingdom (England)
Project Title: IRF4 and BLIMP1: defining a complex transcriptional switch in B-cell differentiation deregulated in lymphomagenesis
Funds Awarded: £158,558
Location: CNRS, France
Project Title: Genetic modifiers of cancer risk in BRCA1/2 mutation carriers: study of the effect of sequence variants in the genes involved in the nonsense-mediated mRNA decay pathway
Funds Awarded: £103,226
Location: University of Torino, Italy
Project Title: Role of p130Cas adaptor in estrogen receptor and Her2-Neu-mediated tumorigenesis
Funds Awarded: £112,500
Location: Fondazione Santa Lucia, Italy
Project Title: Role of Caspase-8 tyrosine phosphorylation by Src kinases in tumour progression and in tumor resistance to apotosis
Funds Awarded: £52,818
Location: Instituto Superiore di Sanita, Italy
Project Title: Analysis of alternative pathway activated by replication stress in the cancer-prone disease Werner syndrome: implications for a non-toxic therapy of cancer with specific defects in replication fork re
Funds Awarded: £128,526
Location: CNRS, France
Project Title: Regulation of the p53 family member, p63, by E4F1: Role in the renewal and transformation of stratified epithelia
Funds Awarded: £111,903
Location: University of Birmingham, United Kingdom (England)
Project Title: Extending Epstein-Barr virus tropism by transfer infection: mechanism, range and pathogenetic significance of viral transfer from the B cell surface.
Funds Awarded: £171,754
Location: University of Birmingham, United Kingdom (England)
Project Title: Identification of an inherited Wilms' tumour gene
Funds Awarded: £98,951
Location: Technical University Munich, Germany
Project Title: Development of IPMN lesions in a mouse model of pancreatic cancer
Funds Awarded: £128,518
Location: Peter MacCallum Cancer Centre, Australia
Project Title: Molecular characterization of the tumour suppressive properties of mammalian Scribble
Funds Awarded: £134,640
Location: BSRC Alexander Fleming, Greece
Project Title: The role of the post-transcriptional regulator HuR in neoplastic transformation and inflammatory modulation of intestinal cancers
Funds Awarded: £89,443
Location: University Medical Center Utrecht, Netherlands
Project Title: Identification of metastasis genes activated by oncogenic Kras(G12D)
Funds Awarded: £120,295
Location: Centre de Regulacio Genomica, Spain
Project Title: Function of oncogene / tumor suppressor gene products DEK, EWS and LUCA-15 in pre-mRNA splicing regulation
Funds Awarded: £112,103
Location: ACS Inserm Paris V Sainte Anne, France
Project Title: The immune response against dying tumour cells. The implication of TLR4
Funds Awarded: £101,939
Location: University Medical Center Utrecht, Netherlands
Project Title: The impact of human Regulatory T cells on the Graft versus Tumor effect
Funds Awarded: £155,579
Location: Netherlands Cancer Institute, Netherlands
Project Title: Genome-wide insertional mutagenesis screens to identify cancer genes that collaborate with E-cadherin loss in mammary tumourigenesis
Funds Awarded: £176,848
Location: Institute of Cancer Research, United Kingdom (England)
Project Title: Regulation of Apoptosome Assembly
Funds Awarded: £174,253
Location: Institut Pasteur, France
Project Title: Role of the SUMO Pathway in the Maintenance of Genomic Integrity
Funds Awarded: £92,025
Location: University of Bristol, United Kingdom (England)
Project Title: Alternative splice forms of VEGF in cancer – possible value in anti-VEGF therapy.
Funds Awarded: £158,904
Location: The International Agency for Research on Cancer, France
Project Title: Influence of TP53 gene status on the response of breast cancers to anti-hormone therapy
Funds Awarded: £125,300
Location: Erasmus Medical Center, Netherlands
Project Title: Clinical significance of microRNAs in breast cancer
Funds Awarded: £131,428
Location: Forschungszentrum Karlsruhe, Germany
Project Title: Inhibition of action of Bag-1L as a measure of preventing prostate cancer development and metastasis
Funds Awarded: £155,509
Location: Queens University Belfast, United Kingdom (Northern Ireland)
Project Title: Elucidating the importance of cancer cell-derived interleukin-8 in potentiating the bony metastasis of prostate cancer
Funds Awarded: £159,494
Location: University of Newcastle upon Tyne, United Kingdom (England)
Project Title: The Role of Histone Methyltransferase and Demethylase Enzymes in Androgen Receptor Regulation and Prostate Cancer.
Funds Awarded: £163,001
Location: University of Nottingham, United Kingdom (England)
Project Title: Regulation of cancer cell proliferation by the nuclear receptor corepressor Ccr4-Not
Funds Awarded: £147,333
