Projects funded from October 2003
Location: Institute of Cancer Research, England
Project Title: Non-invasive Monitoring of response to novel P13K-targeted therapeutic agents by magnetic resonance spectroscopy
Funds Awarded: £125,692
Location: Lund University, Sweden
Project Title: Heparan sulfate and polyamines as targets for antitumor therapy
Funds Awarded: £127,914
Location: University of Goteborg, Sweden
Project Title: Angiogenesis in tumors: Roles of endothelial guidance and pericyte recruitment.
Funds Awarded: £155,500
Location: MRC Laboratory of Molecular Biology, England
Project Title: The nuclear export function of the APC tumour suppressor
Funds Awarded: £188,763
Location: University of East Anglia, England
Project Title: Characterisation of Non-homologous End-joining of DNA in bacteria
Funds Awarded: £35,522
Location: International Agency for Research on Cancer (IARC), France
Project Title: The role of DNA repair and cell cycle control gene polymorphisms in the development of lung cancer
Funds Awarded: £109,294
Location: Forschungszentrum Karlsruhe, Germany
Project Title: Modulation of androgen receptor action in prostate carcinoma cells by the coactivator Bag-1L
Funds Awarded: £152,997
Location: Cardiff University, Wales
Project Title: Stat3 and tumour suppression, investigating roles in mammary and intestinal epithelia
Funds Awarded: £189,988
Location: International Agency for Research on Cancer (IARC), France
Project Title: Multicentre study of genetic and environmental determinants of Nasopharyngeal Carcinoma in the endemic region of North Africa
Funds Awarded: £96,650
Location: University of Newcastle upon Tyne, England
Project Title: Investigation of the therapeutic potential of novel CDK inhibitors in prostate cancer
Funds Awarded: £83,545
Location: University of Edinburgh, Scotland
Project Title: Exploiting an unique opportunity to study the earliest consequences of tumour suppressor loss in a real tissue
Funds Awarded: £138,765
Location: Institut Pasteur, France
Project Title: SUMO Modification and the Acute Promyelocytic Leukemia-Associated PML Nuclear Bodies
Funds Awarded: £132,000
Location: University of Leicester, England
Project Title: Functions of BCL11A and BCL11B in B- and T-cell malignancies
Funds Awarded: £133,312
Location: University of Dundee, Scotland
Project Title: Translational regulation of p53 expression
Funds Awarded: £118,365
Location: University of Cambridge School of Clinical Medicine, England
Project Title: A sibling pair study to identify Barrett's oesophagus susceptibility genes
Funds Awarded: £86,000
Location: Medical Research Council Laboratory of Molecular Biology, England
Project Title: Control of cell proliferation by intercellular signalling
Funds Awarded: £135,414
Location: University of Dundee, Scotland
Project Title: SUMO-2 modification of the "DEAD box" protein p68: Functional analysis and role in tumour development
Funds Awarded: £72,150
Location: National Institute for Medical Research, England
Project Title: Structural and functional analysis of chromatin regulation by histone methyltransferases and implications for anti-cancer drugs
Funds Awarded: £134,588
Location: Tel Aviv University, Israel
Project Title: Antagonistic activity of the human frizzled 6 (Hfz6) receptor on Wnt signaling
Funds Awarded: £89,200
Location: The University of Kent at Canterbury, England
Project Title: The Role of the Neuregulin gene family in Prostate Cancer
Funds Awarded: £124,444
Location: University of Leeds, England
Project Title: Identification of target(s) for chemoprevention of colorectal cancer by indomethacin
Funds Awarded: £120,225
Location: European Institute of Oncology, Italy
Project Title: Role of the Polycomb gene EZH2 in cancer and cell proliferation
Funds Awarded: £117,763
Location: International Agency for Research on Cancer, France
Project Title: Functional & genetic study of Trrap in oncogenic transformation & tumour development
Funds Awarded: £89,890
Location: Hammersmith Hospital, England
Project Title: Identification of AP-2y target genes in breast tumour derived cell lines using ChIP
Funds Awarded: £138,971
Location: University College London, England
Project Title: Regulation of HPV variant gene expression and cervical carcinogenesis by the Brn-3a transcription factor
Funds Awarded: £120,774
Location: National Institute for Medical Research, England
Project Title: The role of NF-kB2 in cell transformation by the EBV Latent Membrane Protein 1
Funds Awarded: £132,932
Location: Richard Dimbleby / Cancer Research UK Labs, England
Project Title: Use of a novel organotypic transplantation model to determine role of the integrin xvb6 in SCC invasion in vivo
Funds Awarded: £140,413
Location: Trinity College, University of Dublin, Ireland
Project Title: Development of novel calix (4) sugars as lectin-specific drug delivery systems
Funds Awarded: £75,843
Location: The University of Hong Kong, Hong Kong
Project Title: Characterization of novel tumour suppressor genes, DLC1 and DLC2 genes, in liver cancer
Funds Awarded: £112,500
Location: University of London, England
Project Title: The role of Ax1, a receptor tyrosine kinase, in epidermal squamous carcinogenesis
Funds Awarded: £84,190
Location: University of London, England
Project Title: Synthesis & evaluation of covalently dimerised redox-sensitive peptide conjugates as AP-1 transcriptional factor inhibitors
Funds Awarded: £84,743
Location: European Institute of Oncology, Italy
Project Title: Role of Nucleophosmin in tumor development
Funds Awarded: £92,287
Location: University of Dundee, Scotland
Project Title: The cellular function of SNIP1, a nuclear repressor of p53 and NF-kB transcriptional activity
Funds Awarded: £34,130
Location: University College London, England
Project Title: Regulation of cell proliferation and transformation by RhoE/Rnd3
Funds Awarded: £133,876
Location: Peter MacCallum Cancer Institute, Australia
Project Title: The role of the D1g/Scrib/Lg1 pathway in cancer
Funds Awarded: £123,316
Location: The Hebrew University of Jerusalem, Israel
Project Title: P53 involvement in apoptosis and cell cycle arrest - a functional genomic approach
Funds Awarded: £144,866
Location: University of Patras, Greece
Project Title: Geminin, a negative regulator of cell division: gene inactivation in mice and functional analysis
Funds Awarded: £66,713
Location: University College London, England
Project Title: Characterisation of the protein kinase activity of PI 3-kinase
Funds Awarded: £127,776
Location: Cancer Research UK London Institute, England
Project Title: Mapping the role of Beta-catenin in stem cell fate and tumourigenesis within the mammalian epidermis
Funds Awarded: £38,448
Location: St Andrews University, Scotland
Project Title: Functional characterisation of the archaeal Nucleotide Excision Repair protein XPF
Funds Awarded: £60,950
Location: Hebrew University - Hadassah Medical School, Israel
Project Title: The role of VICKZ proteins in cell migration and metastasis in colorectal carcinoma cells
Funds Awarded: £99,535
